![]() ![]() memory or executive functions) with their own specialized brain modules is an open question in the literature. However, whether socio-cognitive skills (including empathy) are functions independent from other nonsocial cognitive functions (e.g. The neuroanatomical bases of these abilities in humans have been most consistently identified in a circuit comprising the insula, prefrontal cortices, superior temporal gyrus, temporoparietal junction and temporal poles, anterior cingulate cortex, and the inferior parietal lobules 1, 2, 3, which are also regions that have been linked to the mirror neuron system 4. Emotional empathy concerns the ability to feel and share the emotional experience of others (i.e. Cognitive empathy refers to cognitive ability of understanding of another person’s perspective and feelings (i.e. The two main neurocognitive components of empathic abilities are cognitive and emotional empathy. These findings allow to extend the traditional cortico-centric view of cognitive empathy to the cerebellar regions in patients with neurodegenerative disorders and suggest that the cerebellum may play a more prominent role in social cognition than previously appreciated.Įmpathy describes the ability to understand and share other’s emotional feelings and is fundamental to our emotional and social lives 1. At subcortical level, empathy scores were positively correlated with gray matter volume in the amygdala, hippocampus and the cerebellum. Lower levels of empathy were associated with an increased atrophy in fronto-temporal cortical structures. ![]() Twenty-seven participants with CBS and 31 with PSP were evaluated using Interpersonal Reactivity Index scales in correlation with gray matter atrophy using a voxel-based morphometry approach. We aimed to investigate the topographical distribution of morphometric brain changes associated with empathy in Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS) patients. Loss of empathy is an early and central symptom of frontotemporal lobar degeneration spectrum diseases. ![]()
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